A new study from Prof. Bal Khakh’s lab identifies astrocyte gene expression changes in Huntington’s Disease, paving the way for identification of therapeutic targets.
Astrocyte molecular signatures in Huntington’s disease was published in
Science Translational Medicine 16 Oct 2019: Vol. 11, Issue 514.
The study is also covered by UCLA Health News
Jun Nagai and colleagues in Prof. Bal Khakh’s lab published in Cell that astrocytes, non-neuronal cells in the brain, regulate behaviors including hyperactivity and attention by promoting new connections between neurons. Hyperactivity with Disrupted Attention by Activation of an Astrocyte Synaptogenic Cue Cell Volume 177, Issue 5, 16 May 2019, Pages 1280-1292.e20 (PDF of article)
In Nature Immunology
faculty members Sonal Srikanth and Yousang Gwack
report a new role for a Ca2+ sensor molecule (STIM1)
to keep the immune system in check by retaining STING (stimulator of interferon genes) in the ER.
STIM1 moonlights as an anchor for STING Nature Immunology 20, 152–162 (2019)
Please join us in welcoming Assistant Professors Lindsay De Biase, Ph.D., and Laura DeNardo, Ph.D., to the Physiology team!
You can read the Department's 2018 accomplishments in the PDF:
2018 Department of Physiology Highlights
Assistant or Associate Professor
DeNardo Lab Open Positions
Postdoctoral Scholar Position
De Biase Lab Open Positions
“From Science of the Heart to the Heart of Science:What Science Can (And Can’t) Tell Us About the World We Live In”” (Link to PDF)
James Weiss, M.D.
“TBA”
