Physiology seeks to understand biological function spanning the range from molecular mechanisms to medical problems.
No other field has such an important task or is as cross-disciplinary in nature.
The Department of Physiology is an internationally recognized research center in which this broad perspective is collaboratively
embraced by the entire faculty.
Areas of systems level investigation include the cardiovascular, gastrointestinal, endocrine, immune and central nervous systems.
We also explore cellular processes such as synaptic transmission, the immune response and muscle excitation-contraction coupling
as well as molecular mechanisms of ion channels and transporters.
At the level of disease, efforts are focused on spinocerebellar ataxia, epilepsy, blindness, cardiac hypertrophy and failure, diabetes,
immune deficiencies, muscular dystrophy, channelopathies, transport deficiencies and others.
Research approaches are multidisciplinary, including electrophysiology and biophysics, molecular, cellular and whole-animal imaging,
proteomics and X-ray crystallography Moreover, the Department has a strong track record of being at the forefront of emerging new approaches.
There are active collaborative ties with clinical departments and institutes throughout the David Geffen School of Medicine,
including the Cardiovascular Research Laboratory and the Departments of Medicine, Pharmacology, Neurology and Anesthesiology.
Recent Publications of Physiology Faculty
Nancy Wayne, PhD and her lab's research have been highlighted in the February 01, 2016 issue of UCLA Newsroom.
Chemical used to replace BPA in plastic accelerates embryonic development, disrupts reproductive system
Junctophilin-4, a component of the endoplasmic reticulum-plasma membrane junctions, regulates Ca2+ dynamics in T cells.
Woo JS, Srikanth S, Nishi M, Ping P, Takeshima H, Gwack Y.
Proc Natl Acad Sci U S A. 2016 Mar 8;113(10):2762-7. doi: 10.1073/pnas.1524229113. Epub 2016 Feb 29.
UCLA scientists receive prestigious BRAIN Initiative grant from NIH
Baljit S. Khakh, PhD is one of the five UCLA scientists who have received a grant from the National Institutes of Health for a study that could provide a better understanding of how neural circuits in the brain process, encode, store and retrieve information.
Muscleblind-Like 1 and Muscleblind-Like 3 Depletion Synergistically Enhances Myotonia by Altering Clc-1 RNA Translation.
Choi J, Personius KE, DiFranco M, Dansithong W, Yu C, Srivastava S, Dixon DM, Bhatt DB, Comai L, Vergara JL, Reddy S.
EBioMedicine. 2015 Sep;2(9):1034-47.
UCLA Physiology Department Open Positions
Assistant Project Scientist