Dr. Tintut earned her Ph.D. in the Department of Biochemistry at University of California, Los Angeles in 1995. She has since joined the David Geffen School of Medicine faculty. She is also a Director of Physiology Teaching Laboratory and Safety Officer in the Department of Physiology.
We investigate the regulatory mechanisms of inflammation on biomineralization in artery wall, aortic valve and bone using in vitro cell culture systems and mouse models.
Lim Jina J, Li Xin, Lu Jinxiu, Pedego Taylor M, Demer Linda, Tintut Yin Protective Role of Smad6 in Inflammation-Induced Valvular Cell Calcification, Journal of cellular biochemistry, 2015; 116(8); 2354-64.
Li Xin, Garcia Jamie, Lu Jinxiu, Iriana Sidney, Kalajzic Ivo, Rowe David, Demer Linda, Tintut Yin Mechanism of hyperlipidemia-induced parathyroid hormone (PTH) resistance: A role of PTH receptor and reactive oxygen species in preosteoblasts Journal of cellular biochemistry, 2013; 115(1);179-88.
Pirih Flavia, Lu Jinxiu, Ye Fei, Bezouglaia Olga, Atti Elisa, Ascenzi Maria-Grazia, Tetradis Sotirios, Demer Linda, Aghaloo Tara, Tintut Yin Adverse effects of hyperlipidemia on bone regeneration and strength Journal of bone and mineral research :the official journal of the American Society for Bone and Mineral Research, 2012; 27(2): 309-18.
Tintut Y, Patel J, Parhami F, Demer L L Tumor necrosis factor-alpha promotes in vitro calcification of vascular cells via the cAMP pathway Circulation, 2000; 102(21): 2636-42.