Dr. John Tormey
Professor and Vice-Chair
53-231 CHS
310-825-6573
jtormey@mednet.ucla.edu

Research Interests:

Medical education and curriculum development. (Co-Chair, Medical Education Committee)
Excitation-contraction coupling in cardiac muscle, epithelial biology.

Representative Publications:

Wheeler-Clark, E. S. and Tormey, J. McD. Electron probe x-ray microanalysis of sarcolemma and junctional sarcoplasmic reticulum in rabbit papillary muscles: Low sodium-induced calcium alterations. Circ. Research 60:246-250, 1987.

Walsh, L G. and Tormey, J. McD. Subcellular electrolyte shifts during in vitro myocardial ischemia and reperfusion. Am. J. Physiol. 255:H917-928, 1988.

Tormey, J. McD. and Goodnight, R.C. (1993). Parallel calcium release and reuptake by corbular and junctional SR in beating heart. Biophys J. 64:A120.

Miller, T.W., and Tormey, J. McD. (1993). Calcium displacement by lanthanum in subcellular compartments of rat ventricular myocytes: characterization by electron probe microanalysis. Cardiovasc. Res. 27:2106-2112.

Representative Publications:

Chen, B.M. and Grinnell, A.D. (1997) Kinetics, Ca++ dependence, and biophysical properties of integrin-mediated mechanical modulation of transmitter release from frog motor neerve terminals. J. Neurosci.  17:904-916

Yazejian, B.M., Sun, X.-P., and Grinnell, A.D. (2000) Tracking presynaptic Ca++ dynamics during neurotransmitter release with Ca++-activated K+ channels. Nature Neurosci. 3:566-571.

Sun, V.-P., Yazejian, B, and Grinnell, A.D. (2004) Electrophysiological properties of BK channels in Xenopus motor nerve terminals. J. Physiol. 557:207-228

Synapse in Xenopus 
Nerve-muscle cell culture

Freeze-etch of frog nmj