Dr. Arthur Peskoff
Adjunct Professor
63-378 BRI
310-825-7870
apeskoff@ucla.edu

 

Research Interests:

Models of calcium movement in neuromuscular junctions and heart cells; synaptic transmission; electro-diffusion models; electric potential in membranes, cells and syncytia.

Representative Publications:

Peskoff, A. (1979). Electric potential in three-dimensional electrically syncytial tissues. Bull. Math. Biol. 41:163-181.

Peskoff, A. and Bers, D. M. (1988). Electrodiffusion of ions approaching the mouth of a conducting membrane channel. Biophys. J. 53:863-875.

Peskoff, A., Post, J. A., and Langer, G. A. (1992). Sarcolemmal calcium binding sites in heart II. Mathematical model for diffusion of calcium released from the sarcoplasmic reticulum into the diadic region. J. Membrane Biol. 129:59-69.

Peskoff, A. and Langer, G. A. (1998). Calcium concentration and movement in the ventricular cardiac cell during an excitation-contraction cycle. Biophys. J. 74:153-174.

DiGregorio, D.A., Peskoff, A. and Vergara, J. L. (1999). Measurement of action-potential induced presynaptic calcium domains at a cultured neuromuscular junction. J. Neurosci., in press.

Representative Publications:

Chen, B.M. and Grinnell, A.D. (1997) Kinetics, Ca++ dependence, and biophysical properties of integrin-mediated mechanical modulation of transmitter release from frog motor neerve terminals. J. Neurosci.  17:904-916

Yazejian, B.M., Sun, X.-P., and Grinnell, A.D. (2000) Tracking presynaptic Ca++ dynamics during neurotransmitter release with Ca++-activated K+ channels. Nature Neurosci. 3:566-571.

Sun, V.-P., Yazejian, B, and Grinnell, A.D. (2004) Electrophysiological properties of BK channels in Xenopus motor nerve terminals. J. Physiol. 557:207-228

Synapse in Xenopus 
Nerve-muscle cell culture

Freeze-etch of frog nmj