Dr. Diane Papazian
Professor
53-159 CHS
310-206-7043
papazian@mednet.ucla.edu
Visit My Lab

Research Interests:

Our research focuses on the electrical excitability of the brain ranging from molecules to behavior. We are investigating the function of voltage-gated ion channels that confer excitability on neurons, the effect of channel properties on cell and circuit firing patterns, the neural control of behavior, and the relationship between spike activity and neuronal viability.

Representative Publications:

Issa, F.A., Mazzochi, C., Mock, A.F., and Papazian, D.M. (2011) Spinocerebellar ataxia type 13 mutant potassium channel alters neuronal excitability and causes locomotor deficits in zebrafish. J. Neurosci., in press.

Issa, F.A., O'Brien G., Kettunen, P., Sagasti, A., Glanzman, D.L., and Papazian, D.M. (2011) Neural circuit activity in freely-behaving zebrafish (Danio rerio). J. Exp. Biol. 214, 1028-1038.

Mock, A.F.,* Richardson, J.L.,* Hsieh, J.-Y., Rinetti, G., and Papazian, D.M. (2010) Functional effects of spinocerebellar ataxia type 13 mutations are conserved in zebrafish Kv3.3. BMC Neurosci. 11, 99. (*equal contributors)

Lin, M.A., Abramson J., and Papazian, D.M. (2010) Transfer of ion binding site from ether-à-go-go to Shaker: Mg2+ binds to resting state to modulate channel opening. J. Gen. Physiol. 135, 415-431.

Link to my complete PubMed bibliography