Dr. Gregory Brent
Professor (In Residence)
VA Bldg. 111D
310-268-3735
gbrent@ucla.edu

Research Interests:

Gene regulation by nuclear acting hormones, especially thyroid hormone and retinoic acid

Representative Publications:

Liu,YY, Brent GA. Thyroid hormone-dependent gene expression in differentiated embryonic stem cells and embryonal carcinoma cells: identification of novel thyroid hormone target genes by DNA microarray analysis.Endocrinology 2005; 142:776-783.

Kogai T, Kanamoto Y, Che LH, Taki K, Moatamed F, Schultz J, Brent GA. Systemic retinoic acid treatment induces sodium/iodide symporter and radioiodide uptake in breast cancer models. Cancer Res 2004; 64:415-422.

Liu, Y.Y., Schultz J.J., Brent GA. A thyroid hormone receptor alpha gene mutation (P398H) is associated with visceral adiposity and impaired catecholamine-stimulated lipolysis in mice. J Biol Chem 2003; 278:38913-38920.